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KMID : 1040420180220020081
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Childhood Kidney Diseases
2018 Volume.22 No. 2 p.81 ~ p.85
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A Pediatric Case of Inflammatory Bowel Disease with Renal Amyloidosis
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Hyun Hye-Sun
Park Eu-Jin
Kim Ji-Hyun
Cho Myung-Hyun
Kang Hee-Gyung
Moon Jin-Soo
Moon Kyung-Chul
Ha Il-Soo
Cheong Hae-Il
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Abstract
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Amyloidosis is a rare disease that results from the deposition of extracellular protein in various body tissues, causing progressive organ dysfunction. Secondary renal amyloidosis is a rare but serious complication of chronic inflammatory bowel disease, particularly in patients with Crohn’s disease or ulcerative colitis. We report a case of secondary renal amyloidosis in a pediatric patient who reported a 16-year history of “very early onset inflammatory bowel disease”. Intensive treatment including repeated infliximab infusions improved clinical parameters of inflammatory bowel disease, although renal dysfunction showed progression. Amyloidosis should be considered in patients with IBD, particularly if they suffered disease progression.
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KEYWORD
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Renal amyloidosis, Crohn’s disease, Very early onset inflammatory bowel disease
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